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State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
H2O + tripolyphosphate <=> phosphate + diphosphate 2.5.1.6 methionine adenosyltransferase
3.6.1.11 exopolyphosphatase
3.6.1.14 adenosine-tetraphosphatase
3.6.1.25 triphosphatase
3.6.1.28 thiamine-triphosphatase





reduced_rubredoxin + O2- + H+ <=> rubredoxin + H2O2 1.15.1.2 superoxide reductase

UDP-glucose + D-fructose <=> sucrose + UDP + H+ 2.4.1.13 sucrose synthase
2.4.1.14 sucrose-phosphate synthase


pyranose + NADP+ <=> an_aldono-1,5-lactone + NADPH + H+ 1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]

phenyl_acetate + H2O <=> phenol + acetate + H+ 3.1.1.1 carboxylesterase
3.1.1.2 arylesterase
3.1.1.55 acetylsalicylate deacetylase
3.1.1.6 acetylesterase
3.1.1.73 feruloyl esterase
3.1.1.8 cholinesterase
3.1.8.1 aryldialkylphosphatase
3.1.8.2 diisopropyl-fluorophosphatase
3.7.1









thioredoxin + H2O2 <=> thioredoxin_disulfide + H2O 1.11.1.15 peroxiredoxin
1.11.1.20 prostamide/prostaglandin F2alpha synthase
1.11.1.24 thioredoxin-dependent peroxiredoxin
1.11.1.25 glutaredoxin-dependent peroxiredoxin
1.11.1.7 peroxidase





NADPH + H+ + O2 <=> NADP+ + H2O 1.6.3.2 NAD(P)H oxidase (H2O-forming)

ADP + diphosphate <=> ATP + phosphate 2.7.4.1 polyphosphate kinase
2.7.4.3 adenylate kinase
2.7.7.4 sulfate adenylyltransferase



H+ + H2O2 + NADH <=> H2O + NAD+ 1.11.1.1 NADH peroxidase
1.11.1.11 L-ascorbate peroxidase
1.11.1.16 versatile peroxidase
1.11.1.2 NADPH peroxidase
1.11.1.26 NADH-dependent peroxiredoxin
1.11.1.5 cytochrome-c peroxidase
1.11.1.6 catalase
1.11.1.7 peroxidase
1.14.12.17 nitric oxide dioxygenase









O2- + H+ <=> H2O2 + O2 1.15.1.1 superoxide dismutase
1.7.2.1 nitrite reductase (NO-forming)


CoA + NAD+ <=> CoA-disulfide + NADH + H+ 1.8.1.14 CoA-disulfide reductase
1.8.1.8 protein-disulfide reductase
1.8.1.M1



(S)-2-haloacid + H2O <=> (R)-2-hydroxyacid + acceptor + H+ 3.8.1.10 2-haloacid dehalogenase (configuration-inverting)
3.8.1.2 (S)-2-haloacid dehalogenase


(2R)-octan-2-yl_sulfate + H2O <=> (S)-2-octanol + sulfate + H+ 3.1.6.19 (R)-specific secondary-alkylsulfatase

IDP + H2O <=> IMP + phosphate + H+ 3.6.1.5 apyrase
3.6.1.6 nucleoside diphosphate phosphatase
3.6.1.64 inosine diphosphate phosphatase



ITP + H2O <=> IMP + diphosphate + H+ 3.6.1
3.6.1.66 XTP/dITP diphosphatase
3.6.1.8 ATP diphosphatase
3.6.1.9 nucleotide diphosphatase




arsenate + reduced_glutaredoxin <=> arsenite + thioredoxin_disulfide 1.20.4.1 arsenate reductase (glutathione/glutaredoxin)

phenyl_acetate + H2O <=> phenol + acetate + H+ 3.1.1.1 carboxylesterase
3.1.1.2 arylesterase
3.1.1.55 acetylsalicylate deacetylase
3.1.1.6 acetylesterase
3.1.1.73 feruloyl esterase
3.1.1.8 cholinesterase
3.1.8.1 aryldialkylphosphatase
3.1.8.2 diisopropyl-fluorophosphatase
3.7.1









formaldehyde + NAD+ + H2O <=> formate + NADH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.21 glycolaldehyde dehydrogenase
1.2.1.22 lactaldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.32 aminomuconate-semialdehyde dehydrogenase
1.2.1.46 formaldehyde dehydrogenase
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.65 salicylaldehyde dehydrogenase
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase










thiosulfate + cyanide <=> H+ + sulfite + thiocyanate 2.8.1.1 thiosulfate sulfurtransferase
2.8.1.2 3-mercaptopyruvate sulfurtransferase


CoA + NADP+ <=> CoA-disulfide + NADPH + H+ 1.8.1.10 CoA-glutathione reductase
1.8.1.14 CoA-disulfide reductase
1.8.4.2 protein-disulfide reductase (glutathione)



phenyl_acetate + H2O <=> phenol + acetate + H+ 3.1.1.1 carboxylesterase
3.1.1.2 arylesterase
3.1.1.55 acetylsalicylate deacetylase
3.1.1.6 acetylesterase
3.1.1.73 feruloyl esterase
3.1.1.8 cholinesterase
3.1.8.1 aryldialkylphosphatase
3.1.8.2 diisopropyl-fluorophosphatase
3.7.1









UDP-glucose + H2O + NAD+ <=> UDP-glucuronate + NADH + H+ 1.1.1.22 UDP-glucose 6-dehydrogenase

H2O2 <=> H2O + O2 1.11.1.10 chloride peroxidase
1.11.1.21 catalase-peroxidase
1.11.1.6 catalase
1.14.18.1 tyrosinase




NADH + H+ + O2 <=> NAD+ + H2O2 1.11.1.6 catalase
1.11.2.2 myeloperoxidase
1.17.3.2 xanthine oxidase
1.3.1.95 acrylyl-CoA reductase (NADH)
1.6.3.1 NAD(P)H oxidase (H2O2-forming)
1.6.3.3 NADH oxidase (H2O2-forming)
1.6.99.3 NADH dehydrogenase
1.8.1.4 dihydrolipoyl dehydrogenase








reduced_rubredoxin + NADP+ + H+ <=> oxidized_rubredoxin + NADPH 1.18.1.1 rubredoxin---NAD+ reductase
1.18.1.4 rubredoxin---NAD(P)+ reductase


ATP + IDP <=> ITP + ADP 2.7.4.6 nucleoside-diphosphate kinase

O2 + Cl- <=> Chlorite 1.13.11.49 chlorite O2-lyase

benzoate + CoA + ATP <=> benzoyl-CoA + diphosphate + AMP 6.2.1.2 medium-chain acyl-CoA ligase
6.2.1.25 benzoate---CoA ligase
6.2.1.32 anthranilate---CoA ligase
6.2.1.33 4-chlorobenzoate---CoA ligase




H+ + 1,4-benzoquinone + NADPH <=> hydroquinone + NADP+ 1.1.1.328 nicotine blue oxidoreductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
1.7.1.6 azobenzene reductase
1.8.1.9 thioredoxin-disulfide reductase








R-CHOH-R' + NAD+ <=> acetone + NADH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.B3
1.1.1.B4



Dextran + H2O <=> D-glucose 3.2.1.115 branched-dextran exo-1,2-alpha-glucosidase
3.2.1.48 sucrose alpha-glucosidase
3.2.1.70 glucan 1,6-alpha-glucosidase



H2O + diphosphate <=> H+ + phosphate 3.1.3.1 alkaline phosphatase
3.1.3.2 acid phosphatase
3.6.1.1 inorganic diphosphatase
3.6.1.27 undecaprenyl-diphosphate phosphatase
3.6.1.43 dolichyldiphosphatase
3.6.1.9 nucleotide diphosphatase
3.6.2.1 adenylylsulfatase
7.1.3.1 H+-exporting diphosphatase








2 thiosulfate + decylubiquinone + 2 H+ <=> tetrathionate + decylubiquinol 1.8.5.2 thiosulfate dehydrogenase (quinone)

XTP + H2O <=> H+ + XMP + diphosphate 3.6.1
3.6.1.66 XTP/dITP diphosphatase
3.6.1.9 nucleotide diphosphatase



Chlorate + reduced_acceptor <=> Chlorite + H2O + acceptor + H+ 1.7.7.2 ferredoxin---nitrate reductase
1.97.1.1 chlorate reductase


S-adenosyl-L-methionine + 3-demethylubiquinol-9 <=> H+ + ubiquinol-9 + S-adenosyl-L-homocysteine 2.1.1.64 3-demethylubiquinol 3-O-methyltransferase

Fe2+ + H+ + O2 <=> Fe3+ + H2O 1.16.3.1 ferroxidase
1.16.3.3 manganese oxidase


2-hydroxyethylphosphonate + O2 <=> methylphosphonate + HCO3- + H+ 1.13.11.73 methylphosphonate synthase

S-adenosyl-L-methionine + 3-demethylubiquinol-10 <=> H+ + ubiquinol-10 + S-adenosyl-L-homocysteine 2.1.1.64 3-demethylubiquinol 3-O-methyltransferase

an_alkanesulfonate + FMNH2 + O2 <=> an_aldehyde + sulfite + H2O + FMN + H+ 1.14.14.5 alkanesulfonate monooxygenase

methyl_acetate + H2O <=> an_alcohol + a_carboxylate + H+ 3.1.1.1 carboxylesterase

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